OXIDATIVE STRESS AND APOPTOSIS IN HIV-INFECTION - A ROLE FOR PLANT-DERIVED METABOLITES WITH SYNERGISTIC ANTIOXIDANT ACTIVITY

The cascade of events resulting from 'oxidative stress' is markedly similar to that which cart initiate apoptosis, a possible mechanism of immune-cell loss in patients with HIV infection and AIDS. Since primary and secondary metabolites found in plants can act as synergistic antioxidants, and can prevent oxidation-induced cell death, Howard Greenspan and Okezie Aruoma ask whether or not these compounds can be useful in inhibiting viral activation and the death of immune cells in HIV/AIDS.