RADIATION RESISTIVITY OF FROZEN INSULIN SOLUTIONS AND SUSPENSIONS

被引：12

作者：

SOBOLEVA, NN

IVANOVA, AI

TALROSE, VL

TROFIMOV, VI

FEDOTOV, VP

机构：

[1] MOSCOW CHEM PROD BIOL TESTING RES INST,MOSCOW,USSR

[2] MOSCOW EXPTL ENDOCRINOL & HORMON CHEM INST,MOSCOW,USSR

来源：

INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES | 1981年 / 32卷 / 10期

关键词：

Biomedical engineering - DRUG PRODUCTS - Manufacture - STERILIZATION - Radiation Effects;

D O I：

10.1016/0020-708X(81)90024-7

中图分类号：

TL [原子能技术]; O571 [原子核物理学];

学科分类号：

0827 ; 082701 ;

摘要：

A new method of sterilizing medicinal preparations by irradiation with ionizing radiation in the frozen state has recently been suggested. In this work the dependence of the radiation stability of insulin preparations on the conditions of irradiation was investigated. The effect of great increase in radiation resistance of insulin solutions and suspensions after irradiation at low temperatures in the frozen state was observed by absorption spectrophotometry, paper chromatography and biological analysis.

引用

页码：753 / 756

页数：4

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