MECHANISM OF ACTION OF NITROSOUREAS .1. ROLE OF FLUOROETHYLCYTIDINE IN REACTION OF BIS-FLUOROETHYL NITROSOUREA WITH NUCLEIC-ACIDS

被引：28

作者：

TONG, WP ^{[1
]}

LUDLUM, DB ^{[1
]}

机构：

[1] UNION UNIV,ALBANY MED COLL,DEPT PHARMACOL & EXPTL THERAPEUT,ALBANY,NY 12208

来源：

BIOCHEMICAL PHARMACOLOGY | 1978年 / 27卷 / 01期

关键词：

D O I：

10.1016/0006-2952(78)90259-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：77 / 81

页数：5

共 16 条

[1] CHENG CJ, 1972, CANCER RES, V32, P22
[2] DECOMPOSITION OF BCNU (1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA) IN AQUEOUS-SOLUTION
COLVIN, M
COWENS, JW
BRUNDRETT, RB
KRAMER, BS
LUDLUM, DB
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1974, 60 (02) : 515 - 520
[3] CHEMICAL BASIS FOR ANTITUMOR ACTIVITY OF CHLOROETHYLNITROSOUREAS
COLVIN, M
BRUNDRETT, RB
COWENS, W
JARDINE, I
LUDLUM, DB
[J]. BIOCHEMICAL PHARMACOLOGY, 1976, 25 (06) : 695 - 699
[4] EWIG RAG, 1976, P AM ASSOC CANC RES, V17, P147
[5] HALL R, 1971, MODIFIED NUCLEOSIDES, P118
[6] REACTION OF BCNU (1,3-BIS (2-CHLOROETHYL)-1-NITROSOUREA) WITH POLYCYTIDYLIC ACID - SUBSTITUTION OF CYTOSINE RING
KRAMER, BS
FENSELAU, CC
LUDLUM, DB
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1974, 56 (03) : 783 - 788
[7] METHYLATION OF DEOXYRIBONUCLEIC ACID IN CULTURED MAMMALIAN CELLS BY N-METHYL-N'-NITRO-N-NITROSOGUANIDINE - INFLUENCE OF CELLULAR THIOL CONCENTRATIONS ON EXTENT OF METHYLATION AND 6-OXYGEN ATOM OF GUANINE AS A SITE OF METHYLATION
LAWLEY, PD
THATCHER, CJ
[J]. BIOCHEMICAL JOURNAL, 1970, 116 (04) : 693 - &
[8] REACTION OF 1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA WITH SYNTHETIC POLYNUCLEOTIDES
LUDLUM, DB
KRAMER, BS
WANG, J
FENSELAU, C
[J]. BIOCHEMISTRY, 1975, 14 (25) : 5480 - 5485
[9] MICROSOMAL MONO-OXYGENATION OF CARCINOSTATIC 1-(2-CHLOROETHYL)-3-CYCLOHEXYL-1-NITROSOUREA - SYNTHESIS AND IDENTIFICATION OF CIS AND TRANS MONOHYDROXYLATED PRODUCTS
MAY, HE
BOOSE, R
REED, DJ
[J]. BIOCHEMISTRY, 1975, 14 (21) : 4723 - 4730
[10] DECOMPOSITION OF N-(2-CHLOROETHYL)-N-NITROSOUREAS IN AQUEOUS-MEDIA
MONTGOMERY, JA
JAMES, R
MCCALEB, GS
KIRK, MC
JOHNSTON, TP
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (06) : 568 - 571

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