DEFECT IN ZINC UPTAKE BY JEJUNAL BIOPSIES IN ACRODERMATITIS-ENTEROPATHICA

被引：58

作者：

ATHERTON, DJ ^{[1
]}

MULLER, DPR ^{[1
]}

AGGETT, PJ ^{[1
]}

HARRIES, JT ^{[1
]}

机构：

[1] HOSP SICK CHILDREN,LONDON WC1N 3JH,ENGLAND

来源：

CLINICAL SCIENCE | 1979年 / 56卷 / 05期

关键词：

D O I：

10.1042/cs0560505

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

1. In a system in vitro, 65Zn accumulation by jejunal mucosal biopsies from patients with acrodermatitis enteropathica was found to be markedly reduced compared with controls. 2. We suggest that defective uptake of zinc by enterocytes is the primary abnormality responsible for the zinc deficiency underlying this disorder.

引用

页码：505 / 507

页数：3

共 12 条

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