CHARACTERIZATION OF A G-PROTEIN BETA-SUBUNIT GENE FROM THE NEMATODE CAENORHABDITIS-ELEGANS

被引：47

作者：

VANDERVOORN, L ^{[1
]}

GEBBINK, M ^{[1
]}

PLASTERK, RHA ^{[1
]}

PLOEGH, HL ^{[1
]}

机构：

[1] NETHERLANDS CANC INST,DIV CELLULAR BIOCHEM,PLESMANLAAN 121,1066 CX AMSTERDAM,NETHERLANDS

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1990年 / 213卷 / 01期

关键词：

D O I：

10.1016/S0022-2836(05)80118-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The gene encoding the β-subunit of guanine nucleotide binding regulatory proteins (G-proteins) has been cloned from the nematode Caenorhabditis elegans. The predicted 340 amino acid sequence matches the highly conserved amino acid sequences of previously isolated G-protein β-subunits from mammals and Drosophila. The coding region of the C. elegans β-subunit gene, which has been mapped to the C. elegans chromosome II, is interrupted by eight introns. Southern analysis indicates that C. elegans has only one β-subunit gene. A 2·8 kb (1 kb = 103 bases or base-pairs) transcript derived from this gene could be detected. © 1990 Academic Press Limited.

引用

页码：17 / 26

页数：10

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