FUNCTIONALIZATION OF THE METHYL-GROUP OF 2-METHYLINDOLE BY DIRECT GENERATION OF A C,N-DIANION

被引：19

作者：

INAGAKI, S

NISHIZAWA, Y

SUGIURA, T

ISHIHARA, H

机构：

[1] Department of Chemistry, Faculty of Engineering, Gifu University, Yanagido

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 01期

关键词：

D O I：

10.1039/p19900000179

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first method for directly generating C,N-dianion from an alkyl-substituted π-excessive N-hetero-cyclic compound (2-methylindole) has been developed. It involves treatment with 3 equiv. of BuLi and 2 equiv. of ButOK in a particular sequence and results in the functionalization of the 2-methyl group of the indole in a regiospecific manner.

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页码：179 / 180

页数：2

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