ACYCLIC NUCLEOSIDE ANALOGS - SYNTHESIS OF OPEN-RING RIBOSIDE OR DEOXYRIBOSIDE ANALOGS LACKING C(3') OR THE C(3')-C(4') BOND

被引：38

作者：

BRYANT, JD ^{[1
]}

KEYSER, GE ^{[1
]}

BARRIO, JR ^{[1
]}

机构：

[1] UNIV ILLINOIS,SCH CHEM SCI,ROGER ADAMS LAB,URBANA,IL 61801

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 21期

关键词：

D O I：

10.1021/jo01335a033

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Alkyl-1, 3-dioxolanes were treated with trimethylsilyl iodide to generate iodoalkyl (trimethylsilyloxy) ethyl ethers which were used to provide acyclic nucleoside analogues lacking C(3') or the 0(30-0(4') bond. © 1979, American Chemical Society. All rights reserved.

引用

页码：3733 / 3734

页数：2

共 9 条

[1] (S)-9-(2,3-DIHYDROXYPROPYL)ADENINE - ALIPHATIC NUCLEOSIDE ANALOG WITH BROAD-SPECTRUM ANTI-VIRAL ACTIVITY
DECLERCQ, E
DESCAMPS, J
DESOMER, P
[J]. SCIENCE, 1978, 200 (4341) : 563 - 565
[2] ANTI-VIRAL ACTIVITY OF ALIPHATIC NUCLEOSIDE ANALOGS - STRUCTURE-FUNCTION RELATIONSHIP
DECLERCQ, E
HOLY, A
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (05) : 510 - 513
[3] SELECTIVITY OF ACTION OF AN ANTI-HERPETIC AGENT, 9-(2-HYDROXYETHOXYMETHYL)GUANINE
ELION, GB
FURMAN, PA
FYFE, JA
DEMIRANDA, P
BEAUCHAMP, L
SCHAEFFER, HJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (12) : 5716 - 5720
[4] FYFE JA, 1978, J BIOL CHEM, V253, P8721
[5] JUNG ME, 1977, TETRAHEDRON LETT, P4175
[6] DIRECT SYNTHESIS OF DIBENZOCYCLOOCTADIENES VIA DOUBLE ORTHO FRIEDEL-CRAFTS ALKYLATION BY USE OF ALDEHYDE-TRIMETHYLSILYL IODIDE ADDUCTS
JUNG, ME
MOSSMAN, AB
LYSTER, MA
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (19) : 3698 - 3701
[7] JUNG ME, 1978, SYNTHESIS-STUTTGART, P588
[8] QUANTITATIVE DEALKYLATION OF ALKYL ETHERS VIA TREATMENT WITH TRIMETHYLSILYL IODIDE - NEW METHOD FOR ETHER HYDROLYSIS
JUNG, ME
LYSTER, MA
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1977, 42 (23) : 3761 - 3764
[9] KEYSER GE, 1979, TETRAHEDRON LETT, P3263

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