HIGH-CONCENTRATION CULTIVATION OF LACTOCOCCUS-CREMORIS IN A CELL-RECYCLE REACTOR

被引：53

作者：

BIBAL, B ^{[1
]}

VAYSSIER, Y ^{[1
]}

GOMA, G ^{[1
]}

PAREILLEUX, A ^{[1
]}

机构：

[1] INST NATL SCI APPL,CTR TRANSFER BIOTECHNOL MICROBIOL,DEPT GENIE BIOCHIM & ALIMENTAIRE,F-31077 TOULOUSE,FRANCE

来源：

BIOTECHNOLOGY AND BIOENGINEERING | 1991年 / 37卷 / 08期

关键词：

LACTOCOCCUS-CREMORIS; CELL-RECYCLE FERMENTER; CROSS-FLOW FILTRATION; HIGH CELL CONCENTRATION CULTURES;

D O I：

10.1002/bit.260370809

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

High-cell concentration cultivation of Lactococcus cremoris, a homofermentative lactic acid producer, in a cell-recycle fermentor is described. Cross-flow filtration allowing continuous removal of the inhibitory metabolite, the influence of dilution rate on growth was investigated in total or partial cell-recycle cultures. The dependence of growth characteristics on operating conditions was identified and quantified using lactose as the carbon source. Growth kinetics could be described by both lactate removal efficiency and nutrient availability. Based on physiological observations, biomass and lactic acid productivities were predicted in partial cell-recycle cultures.

引用

页码：746 / 754

页数：9

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