HEXADECYLPHOSPHOCHOLINE IN THE TOPICAL TREATMENT OF SKIN METASTASES IN BREAST-CANCER PATIENTS

被引：45

作者：

UNGER, C

PEUKERT, M

SINDERMANN, H

HILGARD, P

NAGEL, G

EIBL, H

机构：

[1] MAX PLANCK INST BIOPHYS CHEM,W-3400 GOTTINGEN,GERMANY

[2] ASTA PHARMA AG,DEPT CANC RES & DEV,FRANKFURT,GERMANY

来源：

CANCER TREATMENT REVIEWS | 1990年 / 17卷 / 2-3期

关键词：

D O I：

10.1016/0305-7372(90)90054-J

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Widespread local recurrence of breast cancer, untreatable by surgery or radiation therapy, can present a serious therapeutic problem predominantly in patients refractory to systemic therapy. In a phase I trial hexadecylphosphocholine, a new agent with high membrane affinity and antineoplastic activity was applied topically to affected skin areas of breast cancer patients. The results provide evidence that hexadecylphosphocholine may be an active agent in the topical treatment of skin metastases. © 1990.

引用

页码：243 / 246

页数：4

共 7 条

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