A NEW 5-MEMBERED RING ANNULATION METHOD BASED ON PD(0)-CATALYZED INTRAMOLECULAR COUPLING OF VINYL IODIDE AND ENOLATE ANION FUNCTIONS

被引：72

作者：

PIERS, E

MARAIS, PC

机构：

[1] Department of Chemistry, University of British Columbia, Vancouver

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 11期

关键词：

D O I：

10.1021/jo00298a014

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Conjugate addition of the cuprate reagent 6 to the enones 7, 11, and 15a-c, followed by treatment of the resultant products with I2 in CH2C12, provides the keto iodides 9, 13, and 17a-c, respectively. Cyclization of the latter substances via a novel Pd(0)-catalyzed coupling process affords the annulation products 10, 14, and 19a-c. © 1990, American Chemical Society. All rights reserved.

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页码：3454 / 3455

页数：2

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