EFFECT OF ORAL 1,25 DIHYDROXYCHOLECALCIFEROL ON CALCIUM AND PHOSPHATE MALABSORPTION IN PRIMARY BILIARY-CIRRHOSIS

被引：12

作者：

FARRINGTON, K ^{[1
]}

EPSTEIN, O ^{[1
]}

VARGHESE, Z ^{[1
]}

NEWMAN, SP ^{[1
]}

MOORHEAD, JF ^{[1
]}

SHERLOCK, S ^{[1
]}

机构：

[1] ROYAL FREE HOSP,DEPT MED,LONDON WC1,ENGLAND

来源：

GUT | 1979年 / 20卷 / 07期

关键词：

D O I：

10.1136/gut.20.7.616

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Changes in calcium and phosphate absorption in response to treatment with small doses of oral 1,25 (OH)2D3 were studied in 10 patients with primary biliary cirrhosis by means of a combined radio-isotope technique. There was a marked improvement in the fractional rates of absorption of calcium (p < 0.01) and phosphate (0.05 < p < 0.1) after treatment. This implies that there is no end organ unresponsiveness to the action of active Vitamin D metabolites at the intestinal level in primary biliary cirrhosis.

引用

页码：616 / 619

页数：4

共 9 条

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