THE ROTENOID CORE STRUCTURE - MODIFICATIONS TO DEFINE THE REQUIREMENTS OF THE TOXOPHORE

被引：21

作者：

CROMBIE, L ^{[1
]}

JOSEPHS, JL ^{[1
]}

CAYLEY, J ^{[1
]}

LARKIN, J ^{[1
]}

WESTON, JB ^{[1
]}

机构：

[1] WELLCOME RES LABS,BERKHAMSTED HP4 2DY,HERTS,ENGLAND

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1992年 / 2卷 / 01期

关键词：

D O I：

10.1016/S0960-894X(00)80645-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A number of modified analogues of the core structure 1, representing the simplest rotenoid, have been made and assayed for their inhibition of NADH dehydrogenase in a blow fly flight-muscle submitochondrial preparation.

引用

页码：13 / 16

页数：4

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