REGULATION OF BIOSYNTHESIS OF SECONDARY METABOLITES .3. INCORPORATION OF 1-14C-ACETIC ACID INTO FATTY ACIDS AND CHLORTETRACYCLINE IN STREPTOMYCES AUREOFACIENS

被引:21
作者
BEHAL, V
CUDLIN, J
VANEK, Z
机构
[1] Department of Biogenesis of Natural Substances, Institute of Microbiology, Czechoslovak Academy of Sciences
关键词
D O I
10.1007/BF02892879
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The rate of fatty acid synthesis with Streptomyces aureofaciens was measured by means of incorporation of 1-14C-acetic acid. The maximum specific rate of incorporation was achieved in the 12th hour. The incorporation rate of the labelled acetate into chlortetracycline was roughly twice that into fatty acids during the production phase. The rate of fatty acid synthesis in the high producing strain was five times that of the low producing one, although the dry weight fatty acid content was almost the same in both the strains. © 1969 Academia, nakladatelství Československé akademie věd.
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页码:117 / &
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