SYNTHESIS OF GLYCOPEPTIDE DERIVATIVES CONTAINING THE 2-ACETAMIDO-N-(L-ASPART-4-OYL)-2-DEOXY-BETA-D-GLUCOPYRANOSYL-AMINE LINKAGE AND HAVING THE AMINO-ACID SEQUENCES 32-34, 33-35, 33-37, AND 33-38 OF BOVINE RIBONUCLEASE

被引：8

作者：

GARG, HG

JEANLOZ, RW

机构：

[1] HARVARD UNIV,SCH MED,DEPT BIOL CHEM,CARBOHYDRATE RES LAB,BOSTON,MA 02115

[2] HARVARD UNIV,SCH MED,DEPT MED,BOSTON,MA 02115

[3] MASSACHUSETTS GEN HOSP,BOSTON,MA 02114

来源：

CARBOHYDRATE RESEARCH | 1979年 / 70卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0008-6215(00)83269-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The synthesis is described of the glycotripeptide derivatives 2-acetamido-3,4,6-tri-O-acetyl-N-[N-(benzyloxycarbonyl)-L--seryl-L-nitroarginyl-L-aspart-4-oyl]-2-deoxy-β-D-glucopyranosylamine, 2-acetamido-3,4,6-tri-O-acetyl-N-[N-(benzyloxycarbonyl)-L-seryl-L-nitroarginyl-L-aspart-1-oyl-(1-p-nitrobenzyl ester)-4-oyl]-2-deoxy-β-D-glucopyranosylamine, and 2-acetamido-3,4,6-tri-O-acetyl-N-[N-(benzyloxycarbonyl)-L-nitroarginyl-L-aspart-1-oyl-(L-leucine methyl ester)-4-oyl]-2-deoxy-β-D-glucopyranosylamine, and of the glycopentapeptide and glycohexapeptide derivatives 2-acetamido-3,4,6-tri-O-acetyl-N-[N-(benzyloxycarbonyl)-L-nitroarginyl-L-aspart-1-oyl-(L-leucyl-L-threonyl-threonyl-Nε-tosyl-L-lysine-(p-nitrobenzyl ester)-4-oyl]-2-deoxy-β-D-glycopyranosylamine and 2-acetamido-3,4,6-tri-O-acetyl-N-[N-(benzyloxycarbonyl)-L-nitroarginyl-L-aspart-1-oyl-(L-leucyl-L-threonyl-Nε-tosyl-L-lysyl-L-aspartic 1,4-di-p-nitrobenzyl ester)-4-oyl]-2-deoxy-β-D-glucopyranosylamine. © 1979.

引用

页码：47 / 58

页数：12

共 22 条

[1]

ALI A, 1971, J ORG CHEM, V36, P3022

[2] A NEW CONVENIENT REAGENT FOR PEPTIDE SYNTHESES [J].