SYNTHESIS OF THE CARBAPENAM RING-SYSTEM VIA CARBENE MEDIATED REARRANGEMENT OF AN N-BENZYLOXY-BETA-LACTAM

被引:17
作者
WILLIAMS, MA [1 ]
MILLER, MJ [1 ]
机构
[1] UNIV NOTRE DAME,DEPT CHEM & BIOCHEM,NOTRE DAME,IN 46556
关键词
D O I
10.1016/S0040-4039(00)98791-4
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The α-diazoester1 in the presence of catalytic Rh2(OAc)4 was converted to the carbapenam2. The synthesis of1 and a proposed mechanism are described. © 1990 Pergamon Press plc.
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页码:1807 / 1810
页数:4
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