A ONE-POT SYNTHESIS OF (E)-5-BROMO-2-PENTENOATE ESTERS

被引：3

作者：

BUNCE, RA

IRWIN, DA

机构：

[1] Department of Chemistry, Oklahoma State University, Stillwater, OK

来源：

SYNTHETIC COMMUNICATIONS | 1990年 / 20卷 / 19期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1080/00397919008051515

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of hydrogen bromide gas to acrolein followed by reaction with a stabilized triphenylphosphoranylidene ylide in benzene solvent affords (E)-5-bromo-2-pentenoate esters in 60-80% yield with greater than 90% selectivity for the E double bond isomer. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：2979 / 2982

页数：4

共 8 条

[1]

FIESER LF, 1967, REAGENTS ORGANIC SYN, V1, P112

[2] INTRAMOLECULAR NITRILE OXIDE CYCLOADDITION ROUTE TO CARBOCYCLICS - A FORMAL TOTAL SYNTHESIS OF PGF2-ALPHA [J].