HIGH AND LOW-ENERGY FAB TANDEM MASS-SPECTROMETRY OF A SERIES OF ANOMERIC AND REGIOISOMERIC 2'-DEOXYRIBOFURANOSYL IMIDAZOLE NUCLEOSIDES

被引：9

作者：

BANOUB, JH

BECCHI, M

DESCOTES, G

FRAISSE, D

HUMBLE, RW

MACKENZIE, G

机构：

[1] UNIV LYON 1,CHIM ORGAN LAB,CNRS,URA 463,F-69622 VILLEURBANNE,FRANCE

[2] HUMBERSIDE POLYTECH,HULL HU6 7RT,ENGLAND

[3] SCA,CNRS,F-69390 VERNAISON,FRANCE

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 1992年 / 11卷 / 04期

关键词：

D O I：

10.1080/07328309208017807

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Positive ion fast atom bombardment mass spectrometry has aided the structural characterisation of a novel series of anomeric and regioisomeric ethyl 5- and 4-amino-2'-deoxy-D-erythro-pentofuranosylimidazole-4- and 5 carboxylate nucleosides. Daughter ion MS/MS analyses (high energy MIKE and low energy MS/MS CAD), of the precursor protonated molecular ions for this series of anomeric and regioisomeric nucleosides have provided distinct and reproducible fingerprint patterns which have permitted discrimination between the individual configurations of the various anomers and regioisomers.

引用

页码：471 / 484

页数：14

共 14 条

[1]

BANOUB J, 1989, Spectroscopy (Amsterdam), V7, P331

[2]

BANOUB J, 1990, ORG MASS SPECTROM, V25, P129

[3] HIGH-ENERGY AND LOW-ENERGY TANDEM MASS-SPECTROMETRY OF OXONIUM IONS FORMED BY FAST-ATOM-BOMBARDMENT IONIZATION OF A SERIES OF DIASTEREOISOMERIC 1,2-TRANS-2-DEOXY-2-IODOGLYCOSYL AZIDES [J].