ANTIGRANULOMA ACTIVITY OF IRAQI WITHANIA-SOMNIFERA

被引：49

作者：

ALHINDAWI, MK ^{[1
]}

ALKHAFAJI, SH ^{[1
]}

ABDULNABI, MH ^{[1
]}

机构：

[1] SCI RES COUNCIL,BIOL RES CTR,DEPT PHARMACOGNOSY & PHARMACOL,BAGHDAD,IRAQ

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1992年 / 37卷 / 02期

关键词：

ANTIINFLAMMATORY ACTIVITY; ANTIGRANULOMA ACTIVITY; WITHANIA-SOMNIFERA; WITHAFERIN-A;

D O I：

10.1016/0378-8741(92)90069-4

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The granuloma-tissue formation inhibiting activity of various fractions of an extract of the aerial parts of Withania somnifera were established using subcutaneous cotton-pellet implantation in rats, Antiinflammatory activity was retained in the methanolic fractions of the plant extract and was comparable to that of a 5 mg/kg dose of hydrocortisone sodium succinate. Activity was attributed to the high content of biologically active steroids in the plant, of which withaferin A is known to be a major component.

引用

页码：113 / 116

页数：4

共 10 条

[1] ANTI-INFLAMMATORY ACTIVITY OF SOME IRAQI PLANTS USING INTACT RATS [J].

ALHINDAWI, MK ;

ALDEEN, IHS ;

NABI, MHA ;

ISMAIL, MA .

JOURNAL OF ETHNOPHARMACOLOGY, 1989, 26 (02) :163-168

[2]

BOWMAN WC, 1980, TXB PHARM

[3]

CHODHA YR, 1976, WEALTH INDIA, P580

[4]

DORFMAN RI, 1965, P SOC EXP BIOL MED, V119, P859

[5] NEW TABLES FOR MULTIPLE COMPARISONS WITH CONTROL [J].

DUNNETT, CW .

BIOMETRICS, 1964, 20 (03) :482-&

[6]

Haynes Jr RC, 1985, PHARMACOL BASIS THER, P1459

[7] ANTI-INFLAMMATORY ACTIVITY OF ERYNGIUM-MARITIMUM L RHIZOME EXTRACTS IN INTACT RATS [J].

LISCIANI, R ;

FATTORUSSO, E ;

SURANO, V ;

COZZOLINO, S ;

GIANNATTASIO, M ;

SORRENTINO, L .

JOURNAL OF ETHNOPHARMACOLOGY, 1984, 12 (03) :263-270

[8]

NUKI G, 1987, DAVIDSONS PRINCIPLES, P560

[9]

SILVERSTRINI B., 1967, EUR J PHARMACOL, V1, P240, DOI 10.1016/0014-2999(67)90010-6

[10]

SOUR KY, 1980, THESIS U BAGHDAD BAG

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