RAPID REORGANIZATION OF CORTICAL MAPS IN ADULT CATS FOLLOWING RESTRICTED DEAFFERENTATION IN RETINA

被引：238

作者：

CHINO, YM ^{[1
]}

KAAS, JH ^{[1
]}

SMITH, EL ^{[1
]}

LANGSTON, AL ^{[1
]}

CHENG, H ^{[1
]}

机构：

[1] VANDERBILT UNIV,DEPT PSYCHOL,NASHVILLE,TN 37240

来源：

VISION RESEARCH | 1992年 / 32卷 / 05期

关键词：

NEURAL PLASTICITY; RETINOTOPIC MAP; VISUAL SYSTEM; ADULT MAMMALIAN BRAIN; CATS;

D O I：

10.1016/0042-6989(92)90021-A

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The retinotopic map in the visual cortex of adult mammals can reorganize in response to a small injury in a restricted region of retina. Although the mechanisms underlying this neural plasticity in adults are not well understood, it is possible that rapid, adaptive alterations in the effectiveness of existing connections play a key role in the reorganization of cortical topography following peripheral deafferentation. In order to test this hypothesis, a small retinal lesion was made in one eye of adult cats and the visual cortex was mapped before and immediately after enucleating the non-lesioned eye. We found that substantial reorganization takes place within hours of enucleation.

引用

页码：789 / 796

页数：8

共 31 条

[1] IMMEDIATE AND CHRONIC CHANGES IN RESPONSES OF SOMATOSENSORY CORTEX IN ADULT FLYING-FOX AFTER DIGIT AMPUTATION [J].