A SIMPLE SYNTHESIS OF GAMMA-KETO AND DELTA-KETO ALPHA-AMINO-ACID DERIVATIVES

被引：14

作者：

AUBRY, N ^{[1
]}

PLANTE, R ^{[1
]}

DEZIEL, R ^{[1
]}

机构：

[1] BIOMEGA INC,2100 CUNARD,LAVAL H7S 2G5,QUEBEC,CANADA

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(00)97050-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The γ and δ-keto α-amino acid derivatives 1a and 1b were prepared from L-aspartic and L-glutamic acid respectively via alkylation of the corresponding β-ketoesters 3a and 3b followed by subsequent ester cleavage and decarboxylation. © 1990.

引用

页码：6311 / 6312

页数：2

共 6 条

[1] C-ACYLATION UNDER VIRTUALLY NEUTRAL CONDITIONS [J].

BROOKS, DW ;

LU, LDL ;

MASAMUNE, S .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1979, 18 (01) :72-74

[2]

Coppola GM, 1987, ASYMMETRIC SYNTHESIS

[3] ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETIC ACID, A VERSATILE REAGENT FOR DETERMINATION OF ENANTIOMERIC COMPOSITION OF ALCOHOLS AND AMINES [J].

DALE, JA ;

DULL, DL ;

MOSHER, HS .

JOURNAL OF ORGANIC CHEMISTRY, 1969, 34 (09) :2543-&

[4] MILD PALLADIUM (0)-CATALYZED DEPROTECTION OF ALLYL ESTERS - A USEFUL APPLICATION IN THE SYNTHESIS OF CARBAPENEMS AND OTHER BETA-LACTAM DERIVATIVES [J].

DEZIEL, R .

TETRAHEDRON LETTERS, 1987, 28 (38) :4371-4372

[5] A NEW DIRECT METHOD FOR THE SYNTHESIS OF ENANTIOMERICALLY PURE PROTECTED ALPHA-AMINO-ACIDS [J].

JACKSON, RFW ;

JAMES, K ;

WYTHES, MJ ;

WOOD, A .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1989, (10) :644-645

[6]

Williams R.M., 1989, ORGANIC CHEM SERIES, V1

← 1 →