VASCULAR ENDOTHELIAL GROWTH-FACTOR VASCULAR-PERMEABILITY FACTOR IS DETECTABLE IN THE SERA OF TUMOR-BEARING MICE AND CANCER-PATIENTS

被引：192

作者：

KONDO, S ^{[1
]}

ASANO, M ^{[1
]}

MATSUO, K ^{[1
]}

OHMORI, I ^{[1
]}

SUZUKI, H ^{[1
]}

机构：

[1] TOAGOSEI CHEM IND,TSUKUBA RES LAB,BIOSCI RES DEPT,TSUKUBA,IBARAKI,JAPAN

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH | 1994年 / 1221卷 / 02期

关键词：

VASCULAR ENDOTHELIAL GROWTH FACTOR; VASCULAR PERMEABILITY FACTOR; SERUM LEVEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; (HUMAN);

D O I：

10.1016/0167-4889(94)90016-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We developed an enzyme-linked immunosorbent assay (ELISA) for vascular endothelial growth factor/vascular permeability factor (VEGF/VPF). The assay revealed that VEGF/VPF levels in the sera of mice were significantly increased from undetectable level by s.c. transplantation with a solid tumor. We also measured VEGF/VPF levels in serum specimens obtained from cancer patients with several types of cancers. VEGF/VPF levels in the sera from cancer patients were significantly higher than those in the sera from the individuals with no sign of cancer.

引用

页码：211 / 214

页数：4

共 21 条

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