INCIDENCE OF HUMAN PARVOVIRUS B19 DNA DETECTION IN BLOOD-DONORS

被引:72
作者
YOTO, Y [1 ]
KUDOH, T [1 ]
HASEYAMA, K [1 ]
SUZUKI, N [1 ]
ODA, T [1 ]
KATOH, T [1 ]
TAKAHASHI, T [1 ]
SEKIGUCHI, S [1 ]
CHIBA, S [1 ]
机构
[1] HOKKAIDO RED CROSS BLOOD CTR,NISHI KU,SAPPORO,HOKKAIDO,JAPAN
关键词
ERYTHEMA INFECTIOSUM; HUMAN PARVOVIRUS B19; DONATED BLOOD; IMMUNOCOMPROMISED HOST; INFECTION VIA TRANSFUSION;
D O I
10.1111/j.1365-2141.1995.tb05427.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1000 serum samples from blood donors were tested for human parvovirus B19 (B19) DNA by a nested PCR assay: six samples were positive for B19 DNA. The frequency was 1/167 (0.6%), considerably higher than previous surveys (0.004-0.03%). Five of the six samples were also positive for anti-B19 IgM, indicating an acute phase of infection. It is recommended to screen for B19 DNA in blood products to prevent transfusion mediated viral infection for those susceptible such as immunocompromised patients and pregnant women.
引用
收藏
页码:1017 / 1018
页数:2
相关论文
共 11 条
  • [1] Azzi A., Ciappi S., Zakvrzewska K., Morfini M., Mariani G., Mannucci P.M., Human parvovirus B19 infection in hemophiliacs first infused with two high‐purity, virally attenuated factor VIII concentrates, American Journal of Hematology., 39, pp. 228-230, (1992)
  • [2] Bartolomei Corci O., Azzi A., Morfini M., Fanci R., Rossi Ferrini P., Human parvovirus infection in haemophiliacs first infused with treated clotting factor concentrates, Journal of Medical Virology, 25, pp. 165-170, (1988)
  • [3] Cohen B.J., Field A.M., Gudnadottir S., Beard S., Barbara J.A.J., Blood donor screening for parvovirus B19, Journal of Virological Methods, 30, pp. 233-238, (1990)
  • [4] Frickhofen N., Young N.S., A rapid method of sample preparation for detection of DNA viruses in human serum by polymerase chain reaction, Journal of Virological Methods, 35, pp. 65-72, (1991)
  • [5] Lefrere J.J., Mariotti M., Thauvin M., B19 parvovirus DNA in solvent/detergent‐treated anti‐haemophilia concentrates, Lancet, 343, pp. 211-212, (1994)
  • [6] McOmish F., Yap P.L., Jordan A., Hart H., Cohen B.J., Simmonds P., Detection of parvovirus B19 in donated blood: a model system for screening by polymerase chain reaction, Journal of Clinkal Microbiology, 31, pp. 323-328, (1993)
  • [7] Mortimer P.P., Luban NX.G, Kelleher J.F., Cohen B.J., Transmission of serum parvovirus‐like virus by clotting‐factor concentrates, Lancet, 2, pp. 482-484, (1983)
  • [8] Yoto Y., Kudoh T., Haseyama K., Suzuki N., Chiba S., Matsunaga Y., Human parvovirus B19 infection in Kawasaki disease, Lancet, 344, pp. 58-59, (1994)
  • [9] Yoto Y., Kudoh T., Suzuki N., Katoh S., Matsunaga Y., Chiba S., Thrombocytopenia induced by human parvovirus B19 infections, European Journal of Haematology, 50, pp. 255-257, (1993)
  • [10] Yoto Y., Kudoh T., Suzuki N., Matsunaga Y., Chiba S., Retrospective study on the influence of human parvovirus B19 infection among children with malignant diseases, Acta Haematologica, 90, pp. 8-12, (1993)