EFFECTS OF VEHICLES AND PRODRUG PROPERTIES AND THEIR INTERACTIONS ON THE DELIVERY OF 6-MERCAPTOPURINE THROUGH SKIN - BISACYLOXYMETHYL-6-MERCAPTOPURINE PRODRUGS

被引：54

作者：

WARANIS, RP ^{[1
]}

SLOAN, KB ^{[1
]}

机构：

[1] UNIV FLORIDA, DEPT MED CHEM, BOX J-485, GAINESVILLE, FL 32610 USA

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1987年 / 76卷 / 08期

关键词：

D O I：

10.1002/jps.2600760803

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：587 / 595

页数：9

共 33 条

[1]

ANDERSON BD, 1980, PHYSICAL CHEM PROPER, pCH7

[2]

BARRY BW, 1983, DERMATOLOGICAL FORMU, P75

[3] SOLUBILITY PARAMETERS [J].

BARTON, AFM .

CHEMICAL REVIEWS, 1975, 75 (06) :731-753

[4]

BIGLER P, 1978, SYNTHESIS-STUTTGART, P593

[5] C-13 MAGNETIC-RESONANCE .26. QUANTITATIVE-DETERMINATION OF TAUTOMERIC POPULATIONS OF CERTAIN PURINES [J].

CHENON, MT ;

PUGMIRE, RJ ;

GRANT, DM ;

PANZICA, RP ;

TOWNSEND, LB .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1975, 97 (16) :4636-4642

[6] A METHOD OF PREDICTING PERCUTANEOUS-ABSORPTION RATES FROM VEHICLE TO VEHICLE - AN EXPERIMENTAL ASSESSMENT [J].

DUGARD, PH ;

SCOTT, RC .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1986, 28 (2-3) :219-227

[7] METHOD FOR ESTIMATING BOTH SOLUBILITY PARAMETERS AND MOLAR VOLUMES OF LIQUIDS [J].

FEDORS, RF .

POLYMER ENGINEERING AND SCIENCE, 1974, 14 (02) :147-154

[8] The reaction between acid halides and aldehydes. II. [J].

French, HE ;

Adams, R .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1921, 43 :651-659

[9]

FROSCH PJ, 1977, CUTANEOUS TOXICITY, P127

[10]

GOULD ES, 1959, MECHANISM STRUCTURE, pCH9

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