INTRAPLEURAL BUPIVACAINE ANALGESIA IN CHEST TRAUMA - A RANDOMIZED DOUBLE-BLIND CONTROLLED TRIAL

被引：12

作者：

KNOTTENBELT, JD

JAMES, MF

BLOOMFIELD, M

机构：

[1] Trauma Unit, Groote Schuur Hospital, Cape Town

[2] Departments of Anaesthesia and Surgery, University of Cape Town

来源：

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | 1991年 / 22卷 / 02期

关键词：

D O I：

10.1016/0020-1383(91)90068-P

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A randomized double-blind study was undertaken to investigate whether 0.25 per cent bupivacaine administered intrapleurally is an effective and reasonably safe method of obtaining analgesia in patients with thoracic injuries. A total of 120 patients complaining of pain after chest injury were entered into the trial. All had thoracostomy tubes already in situ. Of 60 patients who were given the test dose of bupivacaine intrapleurally, 37 obtained satisfactory pain relief for 2 or more hours compared with only 9 of 60 patients who received saline P < 0.000001). Duration of analgesia in the test group (mean 3.9 h) was significantly longer than that in the control group (mean 0.9 h) P < 0.005). There were no important side-effects attributable to the bupivacaine administered. We conclude that intrapleural bupivacaine is an effective and reasonably safe method for obtaining analgesia in patients who have chest drain tubes inserted.

引用

页码：114 / 116

页数：3

共 4 条

[1]

Rocco, Reiestad, Gudman, Et al., Intrapleural administration of local anesthetics for pain relief in patients with multiple rib fractures, Reg. Anaesth., 12, (1987)

[2]

Rosenberg, Scheinin, Lepantalo, Et al., Continuous intrapleural infusion of bupivacaine for analgesia after thoracotomy, Anesthesiology, 67, (1987)

[3]

Seltzer, Larijani, Goldberg, Et al., Intrapleural bupivacaine — a kinetic and dynamic evaluation, Anesthesiology, 67, (1987)

[4]

Stromskrag, Reiestad, Holmqvist, Et al., Intrapleural administration of 0.25%, 0.375%, and 0.5% bupivacaine with epinephrine after cholecystectomy, Anesth. Analg., 67, (1988)

← 1 →