DIASTEREOSELECTIVE ADDITIONS OF ALKYLCUPRATES, ALKENYLCUPRATES, ARYLCUPRATES AND ALLYLCUPRATES TO UNSATURATED CHIRAL IMIDES

被引：48

作者：

MELNYK, O ^{[1
]}

STEPHAN, E ^{[1
]}

POURCELOT, G ^{[1
]}

CRESSON, P ^{[1
]}

机构：

[1] ECOLE NATL SUPER CHIM,SYNTHESE ORGAN LAB,11 RUE PIERRE & MARIE CURIE,F-75231 PARIS 05,FRANCE

来源：

TETRAHEDRON | 1992年 / 48卷 / 05期

关键词：

D O I：

10.1016/S0040-4020(01)88188-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Some diastereoselective conjugate additions of cuprates to chiral unsaturated imides hearing an imidazolidinyl group (from ephedrine and urea) show an impressive stereoselectivity. The chiral (internal auxiliary dependent) group is easily broken and recycled. The steric course of these reactions seems quite general and its development promising in synthesis.

引用

页码：841 / 850

页数：10

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