CONTROLLED RELEASE FROM CYLINDRICAL MICROSTRUCTURES

被引：51

作者：

PRICE, R

PATCHAN, M

机构：

[1] Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, WA, DC

[2] Geo-Centers Inc., Newton, MA

来源：

JOURNAL OF MICROENCAPSULATION | 1991年 / 8卷 / 03期

关键词：

D O I：

10.3109/02652049109069556

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Microtubules formed from diacetylenic phosphatidyl-cholines can be made rugged and solvent resistant through electroless deposition of metals (Rudolph et al. 1990). Once dried tubules can capture a range of materials by capillary action when added to a hydrating medium, thus retaining and controlling the release rates of these materials. We report the encapsulation in tubules of a mixture of tetracycline, epoxy monomers and polymers and their in vitro release kinetics in both dynamic and static environments.

引用

页码：301 / 306

页数：6

共 7 条

[1]

Georger J., Singh A., Price R., Schnur J., Yager P., Schoen P., Helical and tubular microstructures formed from polymerizable phosphatidylcholines, Journal of American Chemical Society, 109, pp. 6169-6175, (1987)

[2]

Price R., Patchan M., Gaber B., Controlled release marine antifouling coatings utilizing tubular microstructures for toxicant encapsulation, (1990)

[3]

Price R., Waynant M., Gaber B., SEM examination of antifouling paint derived from tubular microstructures, (1990)

[4]

Rudolph R., Price R., Singh A., Goins B., Stabilization of Lipid Microstructures

[5]

Fundamentals and Applications, (1990)

[6]

Schnur J., Schoen P., Singh A., Georger J., Price R., Yager P., Biologically derived microstructures, New Technological Applications of Phospholipid Bilayers, Thin Films and Vesicles, pp. 305-320, (1988)

[7]

Yager P., Schoen P., Formation of tubules by polymerized surfactant, Molecular Crystals Liquid Crystals, 166, (1984)

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