HUMAN INFLUENZA-VIRUS RECOGNITION OF SIALYLOLIGOSACCHARIDES

被引：49

作者：

GAMBARYAN, AS

PISKAREV, VE

YAMSKOV, IA

SAKHAROV, AM

TUZIKOV, AB

BOVIN, NV

NIFANTEV, NE

MATROSOVICH, MN

机构：

[1] RUSSIAN ACAD MED SCI,MP CHUMAKOV INST POLIOMYELITIS & VIRAL ENCEPHALIT,MOSCOW 109801,RUSSIA

[2] RUSSIAN ACAD SCI,INST FOOD SUBST,MOSCOW 117813,RUSSIA

[3] ND ZELINSKII INST ORGAN CHEM,MOSCOW 117913,RUSSIA

[4] MM SHEMYAKIN INST BIOORGAN CHEM,MOSCOW 117871,RUSSIA

来源：

FEBS LETTERS | 1995年 / 366卷 / 01期

关键词：

INFLUENZA VIRUS; SIALIC ACID; SIALYLOLIGOSACCHARIDES; SIALYL-LEWIS; PROTEIN-CARBOHYDRATE RECOGNITION;

D O I：

10.1016/0014-5793(95)00488-U

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Sialic acids are essential components of cell-surface receptors utilized by influenza viruses, To evaluate the recognition of asialic sugar parts of the receptor, three representative strains of human influenza A and B viruses were tested for their binding of a panel of sialyloligosaccharides. The highest affinity binding carbohydrate determinants recognized by the viruses in a context of different core structures were Neu5Ac alpha 2-3Gal for the type B virus, Neu5Ac alpha 2-6Gal for the H3 subtype virus, and Neu5Ac alpha 2-6Gal beta 1-4GlcNAc for the H1 subtype virus, Penultimate to these determinants parts of sialyloligosaccharides studied either contributed less significantly to the binding affinity, or interfered with the binding.

引用

页码：57 / 60

页数：4

共 22 条

[1] Paulson, The Receptors, 2, pp. 131-219, (1985)
[2] Wiley, Skehel, Annu. Rev. Biochem., 56, pp. 365-394, (1987)
[3] Suzuki, Nagao, Kato, Suzuki, Matsumoto, Murayama, Biochim. Biophys. Acta, 903, pp. 417-424, (1987)
[4] Rogers, D'Souza, Virology, 173, pp. 317-322, (1989)
[5] Connor, Kawaoka, Webster, Paulson, Receptor Specificity in Human, Avian, and Equine H2 and H3 Influenza Virus Isolates, Virology, 205, pp. 17-23, (1994)
[6] Bergelson, Bukrinskaya, Prokazova, Shaposhnikova, Kocharov, Shevchenko, Kornilaeva, Fomina-Ageeva, Eur. J. Biochem., 128, pp. 467-474, (1982)
[7] Suzuki, Nagao, Kato, Matsumoto, Nerome, Nakajima, Nobusawa, J. Biol. Chem., 261, pp. 17057-17061, (1986)
[8] Suzuki, Nakao, Ito, Watanabe, Toda, Xu, Suzuki, Kobayashi, Kimura, Yamada, Sugawara, Nishimura, Kitame, Nakamura, Deya, Kiso, Hasegawa, Virology, 189, pp. 121-131, (1992)
[9] Muthing, Unland, Heitmann, Orlich, Hanisch, Peter-Katalinic, Knauper, Tschesche, Kelm, Schauer, Lehmann, Glycoconjugate J., 10, pp. 120-126, (1993)
[10] Pritchett, Brossmer, Rose, Paulson, Virology, 160, pp. 502-506, (1987)

← 1 2 3 →