N-EPSILON-CARBOXYMETHYLLYSINE FORMATION BY DIRECT ADDITION OF GLYOXAL TO LYSINE DURING THE MAILLARD REACTION

被引：23

作者：

ALABED, Y

BUCALA, R

机构：

[1] The Picower Institute For Medical Research, Manhasset, NY 11030

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1995年 / 5卷 / 18期

关键词：

D O I：

10.1016/0960-894X(95)00375-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Glyoxal, a retro-aldol cleavage product of the Maillard reaction, is a likely intermediate for the formation of N-epsilon-carboxymethyllysine upon incubation with lysine under physiological conditions.

引用

页码：2161 / 2162

页数：2

共 5 条

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[4] SYNTHESIS AND CHROMATOGRAPHY OF 1,2-DIAMINO-4,5-DIMETHOXYBENZENE, 6,7-DIMETHOXY-2-METHYLQUINOXALINE AND 6,7-DIMETHOXY-2,3-DIMETHYLQUINOXALINE FOR USE IN A LIQUID-CHROMATOGRAPHIC FLUOROMETRIC ASSAY OF METHYLGLYOXAL
MCLELLAN, AC
THORNALLEY, PJ
[J]. ANALYTICA CHIMICA ACTA, 1992, 263 (1-2) : 137 - 142
[5] IDENTIFICATION OF N-2-(1-CARBOXYETHYL)GUANINE (CEG) AS A GUANINE ADVANCED GLYCOSYLATION END-PRODUCT
PAPOULIS, A
ALABED, Y
BUCALA, R
[J]. BIOCHEMISTRY, 1995, 34 (02) : 648 - 655

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