PROFILE AND SEVERITY OF LITHIUM-INDUCED SIDE-EFFECTS IN MENTALLY HEALTHY SUBJECTS

被引：24

作者：

BECH, P ^{[1
]}

THOMSEN, J ^{[1
]}

PRYTZ, S ^{[1
]}

VENDSBORG, PB ^{[1
]}

ZILSTORFF, K ^{[1
]}

RAFAELSEN, OJ ^{[1
]}

机构：

[1] RIGSHOSP,DEPT EAR NOSE & THROAT,DK-2100 COPENHAGEN O,DENMARK

来源：

NEUROPSYCHOBIOLOGY | 1979年 / 5卷 / 03期

关键词：

Lithium; Polyuria; Tremor;

D O I：

10.1159/000117678

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In a double-blind, placebo-controlled, crossover design various side effects (= unwanted effects) during 6 months of therapeutic serum lithium levels (0.7-1.1 mmol/1) to non-psychiatric patients were studied. The side effects were measured by self-rating scales and independent observer rating scales administered every 2-4 weeks throughout the study. After months of treatment, lithium induced hand tremor and thirst/polyuria; however, without any relationship to the serum levels of lithium. The frequency of tremor was highest in patients above the age of 60 years. No initial sedative-like lithium effect was found. © 1979 S. Karger AG, Basel.

引用

页码：160 / 166

页数：7

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