DETECTION OF MONOCLONAL IGM SUBUNITS IN MACROGLOBULINEMIA WALDENSTROM

被引：14

作者：

HANSSON, UB

LAURELL, CB

机构：

[1] Dept. of Clinical Chemistry, Malmö General Hospital, Malmö University of Lund

来源：

SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION | 1969年 / 24卷 / 03期

关键词：

Electrophoretic mobility; Immunoglobulin; Immunoprecipitation; Macroglobulins; Mercaptoethanol; Subunits;

D O I：

10.3109/00365516909080153

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

A serum containing an M-component of IgM type gave on immunoelectrophoresis a biarcuate precipitation line. The anodal arch was produced by subunits of IgM, the other, by polymeric (17 S) IgM. The subunits combined in other optimal proportions with anti IgM than polymeric IgM as shown by e.g. immunoelectrophoresis and antigen-antibody crossed electrophoresis. Changes in immunoprecipitation patterns after reduction with mercaptoethanol of the cathodal arch to a mobility more equal to the anodal arch is one way to trace IgM subunits in plasma. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：199 / &

共 13 条

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