DEPENDENCE ON PH OF PERMEABILITY TOWARDS ELECTROLYTE IONS OF POLY(L-LYSINE-ALT-TEREPHTHALIC ACID) MICROCAPSULE MEMBRANES

被引：16

作者：

MIYAUCHI, E ^{[1
]}

TOGAWA, Y ^{[1
]}

MAKINO, K ^{[1
]}

OHSHIMA, H ^{[1
]}

KONDO, T ^{[1
]}

机构：

[1] FAC PHARMACEUT SCI TOKYO,SHINJUKU KU,TOKYO 162,JAPAN

来源：

JOURNAL OF MICROENCAPSULATION | 1992年 / 9卷 / 03期

关键词：

D O I：

10.3109/02652049209021247

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Permeation of electrolyte ions through poly(L-lysine-alt-terephthalic acid) microcapsule membranes was studied as a function of the pH of the medium at different ionic strengths. When the pH of the medium was varied, the permeation rate for 5-sulphosalicylate anions, as well as phenyltrimethylammonium cations, was slow at pH values lower than 4, showed a sudden and large increase in the pH range between 4 and 6, and thereafter remained unchanged. This remarkable change in the permeation rate was found to be produced by an abrupt increase in the microcapsule size observed in the same pH range. Increase in the ionic strength of the medium at pH values higher than 6 increased the rate of anion permeation but decreased the rate of cation permeation due to increase in the screening effect of salt ions on the negative charges in the microcapsule membranes.

引用

页码：329 / 333

页数：5

共 6 条

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