IN-VITRO ANTIPHAGOCYTIC EFFECT OF MELIA AZEDARACH LEAF EXTRACTS ON MOUSE PERITONEAL-EXUDATE CELLS

被引：17

作者：

COURREGES, MC ^{[1
]}

BENENCIA, F ^{[1
]}

COTO, CE ^{[1
]}

MASSOUH, EJ ^{[1
]}

COULOMBIE, FC ^{[1
]}

机构：

[1] UNIV BUENOS AIRES,FAC SCI,IMMUNOCHEM LAB,BUENOS AIRES,ARGENTINA

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1994年 / 43卷 / 02期

关键词：

MELIA AZEDARACH; AQUEOUS EXTRACT; MURINE MACROPHAGES; PHAGOCYTOSIS; CHEMILUMINESCENCE; ANTIINFLAMMATORY EFFECT;

D O I：

10.1016/0378-8741(94)90010-8

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The effect of Melia azedarach L. (Meliaceae) leaf extract on the phagocytic capability and respiratory burst of mouse peritoneal exudate cells was studied. The extract inhibited the phagocytosis of opsonized sheep erythrocytes. This inhibition was both dose- and time-dependent and reverted 48 h after removing the extract from the culture medium. Furthermore, chemiluminescence in treated cells was also impaired using either receptor (opsonized zymosan) or post-receptor (PMA) stimuli.

引用

页码：135 / 140

页数：6

共 15 条

[1] ANDREI G M, 1985, Revista Argentina de Microbiologia, V17, P187
[2] MELIACINE, AN ANTIVIRAL COMPOUND FROM MELIA-AZEDARACH L, INHIBITS INTERFERON-PRODUCTION
ANDREI, GM
COULOMBIE, FC
COURREGES, MC
DETORRES, RA
COTO, CE
[J]. JOURNAL OF INTERFERON RESEARCH, 1990, 10 (05): : 469 - 475
[3] AN ANTIVIRAL FACTOR FROM MELIA-AZEDARACH L PREVENTS TACARIBE VIRUS ENCEPHALITIS IN MICE
ANDREI, GM
LAMPURI, JS
COTO, CE
DETORRES, RA
[J]. EXPERIENTIA, 1986, 42 (07): : 843 - 845
[4] ACTIVE OXYGEN SPECIES AND THE FUNCTIONS OF PHAGOCYTIC LEUKOCYTES
BADWEY, JA
KARNOVSKY, ML
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1980, 49 : 695 - 726
[5] BHAKUNI DS, 1969, INDIAN J EXP BIOL, V7, P250
[6] PLANTS AS SOURCES OF ANTIMALARIAL-DRUGS .7. ACTIVITY OF SOME SPECIES OF MELIACEAE PLANTS AND THEIR CONSTITUENT LIMONOIDS
BRAY, DH
WARHURST, DC
CONNOLLY, JD
ONEILL, MJ
PHILLIPSON, JD
[J]. PHYTOTHERAPY RESEARCH, 1990, 4 (01) : 29 - 35
[7] PARTIALLY PURIFIED LEAF EXTRACTS OF MELIA-AZEDARACH L INHIBIT TACARIBE VIRUS GROWTH IN NEONATAL MICE
COULOMBIE, FC
ANDREI, GM
LAGUENS, RP
DETORRES, RA
COTO, CE
[J]. PHYTOTHERAPY RESEARCH, 1992, 6 (01) : 15 - 19
[8] CYCLOPHOSPHAMIDE MODULATES ARACHIDONIC-ACID METABOLISM BY PERITONEAL-MACROPHAGES
GIORDANO, M
GEFFNER, JR
PRAT, A
PALERMO, MS
SEREBRINSKY, GP
ISTURIZ, MA
[J]. INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, 1988, 10 (08): : 939 - 944
[9] GOLSTEIN P, 1973, CELL IMMUNOL, V9, P124
[10] LABADIE RP, 1989, PLANTA MED, V55, P339

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