CARNITINE TRANSPORT IN SUB-MITOCHONDRIAL PARTICLES AND RECONSTITUTED PROTEOLIPOSOMES

被引：15

作者：

SCHULZ, H

RACKER, E

机构：

[1] Section of Biochemistry, Molecular and Cell Biology, Cornell University, Ithaca

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 89卷 / 01期

关键词：

D O I：

10.1016/0006-291X(79)90954-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Influx and efflux measurements of carnitine with submitochondrial particles lead to the conclusion that carnitine can cross the inner mitochondrial membrane by either facilitated diffusion or more rapidly by a carnitine-carnitine exchange. Both, the facilitated diffusion and the exchange are inhibited by N-ethylmaleimide or mersalyl at low concentrations. Reconstituted particles prepared from liposomes and either submitochondrial particles or an octyl β-glucoside-solubilized preparation were active in catalyzing carnitine-carnitine exchange. © 1979.

引用

页码：134 / 140

页数：7

共 8 条

[1]

BLAIR PV, 1967, METHOD ENZYMOL, V10, P78

[2]

FRITZ IB, 1963, J LIPID RES, V4, P279

[3] STUDIES ON MECHANISM OF OXIDATIVE PHOSPHORYLATION .7. PREPARATION OF SUBMITOCHONDRIAL PARTICLE (ETPH) WHICH IS CAPABLE OF FULLY COUPLED OXIDATIVE PHOSPHORYLATION [J].