ANTISENSE TECHNOLOGY

被引：9

作者：

CROOKE, ST ^{[1
]}

机构：

[1] ISIS PHARMACEUT, CARLSBAD, CA 92008 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1991年 / 2卷 / 02期

关键词：

D O I：

10.1016/0958-1669(91)90022-W

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

During the past 12 months, significant advances have been reported in the medicinal chemistry, and the pharmacodynamic and pharmacokinetic characterization of oligonucleotides. Advances in medicinal chemistry suggest that the scope for additional modifications as a means of developing therapeutic agents is substantial. This is confirmed by our clearer understanding of the pharmacodynamic and pharmacokinetic properties of oligonucleotides and the increasing number of molecular targets against which they have been shown to be active.

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收藏

页码：282 / 287

页数：6

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