THE MASS OF THE SINDBIS VIRUS NUCLEOCAPSID SUGGESTS IT HAS T = 4 ICOSAHEDRAL SYMMETRY

被引：53

作者：

PAREDES, AM

SIMON, MN

BROWN, DT

机构：

[1] UNIV TEXAS,CELL RES INST,AUSTIN,TX 78713

[2] BROOKHAVEN NATL LAB,DEPT BIOL,UPTON,NY 11973

[3] UNIV TEXAS,DEPT MICROBIOL,AUSTIN,TX 78713

来源：

VIROLOGY | 1992年 / 187卷 / 01期

关键词：

D O I：

10.1016/0042-6822(92)90322-G

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The mass of the nucleocapsid of the alphavirus Sindbis was determined by scanning transmission electron microscopy. The nucleocapsid was found to have an average mass of 10.54 × 106 Da with the largest percentage of particles showing a mass of 10.7 to 10.9 × 106 Da. These data predict that the nucleocapsid contains 240 copies of protein and is a T = 4 icosahedron. © 1992.

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页码：329 / 332

页数：4

相关论文

共 29 条

[1] PROTEIN-PROTEIN INTERACTIONS IN AN ALPHAVIRUS MEMBRANE [J].

ANTHONY, RP ;

BROWN, DT .

JOURNAL OF VIROLOGY, 1991, 65 (03) :1187-1194

[2]

Brown D. T., 1980, TOGAVIRUSES, P473

[3] MORPHOLOGY AND MORPHOGENESIS OF SINDBIS VIRUS AS SEEN WITH FREEZE-ETCHING TECHNIQUES [J].

BROWN, DT ;

WAITE, MRF ;

PFEFFERKORN, ER .

JOURNAL OF VIROLOGY, 1972, 10 (03) :524-+

[4] STRUCTURE OF SINDBIS VIRUS CORE PROTEIN REVEALS A CHYMOTRYPSIN-LIKE SERINE PROTEINASE AND THE ORGANIZATION OF THE VIRION [J].

CHOI, HK ;

TONG, L ;

MINOR, W ;

DUMAS, P ;

BOEGE, U ;

ROSSMANN, MG ;

WENGLER, G .

NATURE, 1991, 354 (6348) :37-43

[5] ORGANIZATION OF THE SINDBIS VIRUS NUCLEOCAPSID AS REVEALED BY BIFUNCTIONAL CROSS-LINKING AGENTS [J].

COOMBS, K ;

BROWN, DT .

JOURNAL OF MOLECULAR BIOLOGY, 1987, 195 (02) :359-371

[6] TOPOLOGICAL ORGANIZATION OF SINDBIS VIRUS CAPSID PROTEIN IN ISOLATED NUCLEOCAPSIDS [J].

COOMBS, K ;

BROWN, DT .

VIRUS RESEARCH, 1987, 7 (02) :131-149

[7] STUDIES ON THE MORPHOLOGY OF ALPHAVIRUSES [J].

ENZMANN, PJ ;

WEILAND, F .

VIROLOGY, 1979, 95 (02) :501-510

[8] INTRACELLULAR-DISTRIBUTION OF SINDBIS VIRUS MEMBRANE-PROTEINS IN BHK-21-CELLS INFECTED WITH WILD-TYPE VIRUS AND MATURATION-DEFECTIVE MUTANTS [J].

ERWIN, C ;

BROWN, DT .

JOURNAL OF VIROLOGY, 1980, 36 (03) :775-786

[9] THE T=4 ENVELOPE OF SINDBIS VIRUS IS ORGANIZED BY INTERACTIONS WITH A COMPLEMENTARY T=3 CAPSID [J].

FULLER, SD .

CELL, 1987, 48 (06) :923-934

[10] CROSSLINKING OF SPIKE GLYCOPROTEINS IN SEMLIKI FOREST VIRUS WITH DIMETHYLSUBERIMIDATE [J].

GAROFF, H .

VIROLOGY, 1974, 62 (02) :385-392