A LONG-RANGE REPEAT CLUSTER IN CHROMOSOME-1 OF THE HOUSE MOUSE, MUS-MUSCULUS, AND ITS RELATION TO A GERMLINE HOMOGENEOUSLY STAINING REGION

被引：22

作者：

PURMANN, L

PLASS, C

GRUNEBERG, M

WINKING, H

TRAUT, W

机构：

[1] Institut für Biologie, Medizinische Universität, D-2400 Lübeck

来源：

GENOMICS | 1992年 / 12卷 / 01期

关键词：

D O I：

10.1016/0888-7543(92)90410-T

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The laboratory mouse C57BL genome contains about 50 copies of a long-range repeat DNA family clustered in the C-D region of chromosome 1. The repeat length is more than 50 kb and includes sequences homologous to at least two mRNAs. There are small differences in the copies of this repeat family such as restriction site mutations and gross differences like rearrangements and insertions of LINE1 elements. A germline homogeneously staining region occurring as a chromosome 1 polymorphism in many feral populations of the house mouse is an amplified version of this long-range repeat cluster. © 1992.

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页码：80 / 88

页数：9

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