AIRBORNE DISSEMINATION OF BURKHOLDERIA (PSEUDOMONAS) CEPACIA FROM ADULT PATIENTS WITH CYSTIC-FIBROSIS

被引:29
作者
HUMPHREYS, H
PECKHAM, D
PATEL, P
KNOX, A
机构
[1] CITY HOSP,DEPT RESP MED,NOTTINGHAM NG5 1PB,ENGLAND
[2] CENT PUBL HLTH LAB,HOSP INFECT LAB,LONDON NW9 5HT,ENGLAND
关键词
D O I
10.1136/thx.49.11.1157
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Background - Burkholderia (Pseudomonas) cepacia is an increasingly important pathogen in patients with cystic fibrosis but it is unclear how it spreads from patient to patient. A study was undertaken to determine whether B cepacia could be recovered from room air occupied by colonised adult patients with cystic fibrosis. Methods - Air samples were obtained consecutively from an enclosed room or isolation cubicle before, during, and after occupation by six patients on nine occasions using a surface air sampler incorporating contact plates with selective medium. Settle plates were also used and sputum from five patients was cultured. Results - B cepacia was recovered from room air during occupation by five of six patients, the number of bacteria ranging from 1 to 158 cfu/m(3) (mean 32 cfu/m(3)). The number of bacteria isolated was greater when patients were coughing. B cepacia persisted in room air on four occasions after the patient left the room, on one occasion for up to 45 minutes. Conclusions - The isolation of B cepacia from the air of rooms occupied by colonised patients suggests that dissemination might occur by aerosol as well as by direct physical contact with patients or contaminated environmental sites.
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页码:1157 / 1159
页数:3
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