Certain discrepancies between theoretical and empirical calibrations of magnetograph response are resolved by recognizing the existence of line profile changes in magnetic regions. Many of the photospheric lines commonly used for magnetic field measurements weaken greatly in magnetic regions outside of sunspots. Unless due account is made of the line profile change, the magnetograph measurements underestimate magnetic flux and field strengths. The 5250.2 Å line is especially sensitive to weakening in magnetic regions. Measurements made with this line underestimate the true field by a factor ranging from about two on the linear portion of the profile to five near the line core. © 1969 D. Reidel Publishing Company.