CURRENT EARLY RESULTS OF PULMONARY THROMBOENDARTERECTOMY FOR CHRONIC PULMONARY-EMBOLISM

被引:30
作者
DAILY, PO [1 ]
DEMBITZSKY, WP [1 ]
IVERSEN, S [1 ]
MOSER, KM [1 ]
AUGER, W [1 ]
机构
[1] SHARP MEM HOSP & REHABIL CTR,SAN DIEGO,CA
关键词
Chronic pulmonary embolism; Elevated pulmonary vascular resistance; Pulmonary hypertension; Pulmonary thromboendarterectomy;
D O I
10.1016/1010-7940(90)90181-X
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Some patients with chronic pulmonary embolism causing severely symptomatic pulmonary hypertension have been managed by heart-lungtransplantation with an associated hospital mortality of 24%. To allow comparison with pulmonary thromboendarterectomy (PTE), we have reviewed the hospital morbidity and mortality in 149 consecutive patients. From 1 October 1984 to 18 September 1989, these patients underwent PTE utilizing astandardized procedure consisting of median sternotomy, cardiopulmonary bypass, deep hypothermia and circulatory arrest for bilateral PTE in 91%(136/149) of the procedures with 7.4% (11/149) and 1.3% (2/149) undergoingright or left PTE, respectively. Ventilator dependency (≥ to 5 days on respirator) occurred in 28.3% (41/146). Hospital mortality (death within 30 days or in hospital) was 11.4% (17/149). Themost common causes of death were respiratory and multiorgan failure, 10(59% of deaths) and acute pulmonary hemorrhage, 3 (17% of deaths). We conclude that PTE with an operative mortality of half that of heart-lung transplantation (11.4% vs. 24%) should be the procedure of choice forsignificantly symptomatic chronic pulmonary embolism. Furthermore, the hazards of immuno suppression and chronic graft rejection are avoided. [Eur J Cardiothorac Surg (1990) 4: 117 - 1231. © Springer-Verlag.
引用
收藏
页码:117 / 123
页数:7
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