1ST EVIDENCE OF SPONTANEOUS DEAMIDATION OF GLUTAMINE RESIDUE VIA CYCLIC IMIDE TO ALPHA-GLUTAMIC AND GAMMA-GLUTAMIC RESIDUE UNDER PHYSIOLOGICAL CONDITIONS

被引：30

作者：

CAPASSO, S

MAZZARELLA, L

SICA, F

ZAGARI, A

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 23期

关键词：

D O I：

10.1039/c39910001667

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

At 37-degrees-C and pH 7.4 the spontaneous deamidation of Gln-peptide proceeds prevalently via a glutarimide intermediate and gives a mixture of alpha-Glu- and gamma-Glu-peptide.

引用

页码：1667 / 1668

页数：2

共 13 条

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