SAFETY AND IMMUNOGENICITY OF A BOOSTER DOSE OF VIBRIO-CHOLERAE CVD-103-HGR LIVE ORAL CHOLERA VACCINE IN SWISS ADULTS

被引：25

作者：

CRYZ, SJ ^{[1
]}

LEVINE, MM ^{[1
]}

LOSONSKY, G ^{[1
]}

KAPER, JB ^{[1
]}

ALTHAUS, B ^{[1
]}

机构：

[1] UNIV MARYLAND,SCH MED,CTR VACCINE DEV,BALTIMORE,MD 21201

来源：

INFECTION AND IMMUNITY | 1992年 / 60卷 / 09期

关键词：

D O I：

10.1128/IAI.60.9.3916-3917.1992

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Adult volunteers received a booster dose (4 x 10(8) CFU) of attenuated Vibrio cholerae CVD 103-HgR oral vaccine 15 or 24 months after primary immunization. The immune response was modest, presumably due to rapid clearance of the vaccine strain by a primed immune system.

引用

页码：3916 / 3917

页数：2

共 7 条

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