IN-VITRO ANTIBACTERIAL SCREENING OF CRYPTOLEPIS-SANGUINOLENTA ALKALOIDS

被引:48
作者
PAULO, A
DUARTE, A
GOMES, ET
机构
[1] UNIV LISBON,FAC PHARM,DEPT PHARMACOGNOSY,P-1600 LISBON,PORTUGAL
[2] UNIV LISBON,FAC PHARM,DEPT MICROBIOL,P-1600 LISBON,PORTUGAL
关键词
CRYPTOLEPIS SANGUINOLENTA; CRYPTOLEPINE; CRYPTOHEPTINE; INDOL ALKALOIDS; ANTIBACTERIAL ACTIVITY;
D O I
10.1016/0378-8741(94)90079-5
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The ethanol and aqueous crude extracts and five alkaloids isolated from the roots of Crytolepis sanguinolenta (Lindl.) Schlechter were screened for antibacterial activity against 7 reference strains by the twofold serial broth microdilution assay. The ethanol extract and the alkaloids cryptolepine and cryptoheptine inhibited the growth of all strains tested except that of Pseudomonas aeruginosa.
引用
收藏
页码:127 / 130
页数:4
相关论文
共 7 条
  • [1] Boakye-Yiadom K., 1979, Q J CRUDE DRUG RES, V17, P78, DOI DOI 10.3109/13880207909067453
  • [2] BOYE GL, 1983, 1ST P INT SEM CRYPT, P37
  • [3] Cimanga K., 1991, Planta Medica, V57, pA98, DOI 10.1055/s-2006-960380
  • [4] GOMES ET, 1993, COMUNICACOES IICT CA, V13, P153
  • [5] HOUGHTON PJ, 1993, INT S PHYTOCHEMICAL
  • [6] PAULO A, 1992, 2ND INT C ETHN UPPS
  • [7] 1991, J ANTIMICROBIAL C SD, V27, P22