WATER BASED SILICONE ELASTOMER CONTROLLED RELEASE TABLET FILM COATING-IV PROCESS EVALUATION

被引：7

作者：

LI, LC

PECK, GE

机构：

[1] PURDUE UNIV,DEPT IND & PHYS PHARM,W LAFAYETTE,IN 47907

[2] UNIV OKLAHOMA,HLTH SCI CTR,COLL PHARM,OKLAHOMA CITY,OK 73190

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1990年 / 16卷 / 03期

关键词：

D O I：

10.3109/03639049009114895

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The processing conditions in an air suspension column were found to be critical in producing controlled release polyethylene glycol-silicone elastomer tablet film coatings. The coating equipment used was also shown to play a major role in determining the permeability of the resultant tablet coatings. This pronounced process dependent phenomenon was explained by the film layering mechanism involved in the formation of the polyethylene glycol containing silicone elastomer coating on tablets. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：415 / 435

页数：21

共 9 条

[1] THE USE OF RESTRICTION ERRORS IN THE DESIGN OF EXPERIMENTS [J].