ISOLATION OF GRAM QUANTITIES OF CONFIGURATIONAL ISOMERS OF CYCLIC NITROSAMINES BY PREPARATIVE LIQUID-CHROMATOGRAPHY

被引：15

作者：

SINGER, SS

SINGER, GM

机构：

[1] Carcinogenesis Program, NCI Frederick Cancer Research Center

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1979年 / 2卷 / 08期

关键词：

D O I：

10.1080/01483917908060132

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Substituted cyclic nitrosamines, e.g., 2, 6-dimethyl-N-nitrosomorpholine and 3, 5-dimethyl-N-nitrosopiperidine are separable into their component configurational isomers by preparative hplc. Gram quantities of the individual isomers sufficient for animal testing were obtained. The identification of contaminants in commercial 2, 6-dimethylmorpholine of purported 99% is discussed. © 1979, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：1219 / 1228

页数：10

共 6 条

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[2]

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[3]

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[5]

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[6]

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