KAINIC ACID AND GLUTAMATE RECEPTOR

被引:98
作者
HALL, JG [1 ]
HICKS, TP [1 ]
MCLENNAN, H [1 ]
机构
[1] UNIV BRITISH COLUMBIA,DEPT PHYSIOL,VANCOUVER V6T 1W5,BC,CANADA
关键词
D O I
10.1016/0304-3940(78)90192-1
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The excitatory effects of microelectrophoretically administered kainic (KAIN) and glutamic (GLUT) acids have been compared on central neurones of the rat in the presence of antagonists of amino acid-induced excitations. Antagonism by both D-α-amino adipic acid (DAA) and glutamic acid diethyl ester (GDEE) of the effects of glutamic acid but not those of kainic acid suggests that these two excitants elevate neuronal firing rate by interaction with differing receptor populations. © 1978.
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页码:171 / 175
页数:5
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