EVALUATION OF A SEMI-AUTOMATIC FILTRATION TECHNIQUE FOR RECEPTOR-BINDING STUDIES

A filtration apparatus, originally designed for cell culture harvesting, has been adapted for the use in receptor binding studies. The incubations are performed in titration plates, with eight rows of twelve wells. The wells in each row are filtered simultaneously on separate filters, and the washing of the filters is performed automatically. The total time consumed per row is less than one minute. The results obtained by using this equipment are in good agreement with those obtained with earlier types of filtration equipments, and the intraassay and interassay variation is very small. © 1979.