A TOTAL SYNTHESIS OF RACEMIC AND OPTICALLY-ACTIVE TERREIN (TRANS-4,5-DIHYDROXY-3-[(E)-1-PROPENYL]-2-CYCLOPENTEN-1-ONE)

被引：54

作者：

KOLB, HC ^{[1
]}

HOFFMANN, HMR ^{[1
]}

机构：

[1] UNIV HANOVER,DEPT ORGAN CHEM,W-3000 HANOVER,GERMANY

来源：

TETRAHEDRON-ASYMMETRY | 1990年 / 1卷 / 04期

关键词：

D O I：

10.1016/S0957-4166(00)86329-6

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Two routes to terrein (1), employing a novel ring contraction of 6-alkoxy-2,3-dihydro-6H-pyran-3-ones (5, 13) are described. Separation into enantiomers was carried out by classical resolution via diastereomeric camphanic acid ester intermediates (14, 15). A new method for cleavage of the 2-(trimethylsilyl)ethyl protecting group in the presence of acid and base sensitive functionality is reported. © 1990.

引用

页码：237 / 250

页数：14

共 26 条

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