SULFONES DERIVED FROM METHYLTHIOPROPENOIC ACID-AMIDES FROM GLYCOSMIS-ANGUSTIFOLIA

被引：37

作者：

GREGER, H ^{[1
]}

HOFER, O ^{[1
]}

ZECHNER, G ^{[1
]}

HADACEK, F ^{[1
]}

WURZ, G ^{[1
]}

机构：

[1] UNIV VIENNA,INST ORGAN CHEM,A-1090 VIENNA,AUSTRIA

来源：

PHYTOCHEMISTRY | 1994年 / 37卷 / 05期

关键词：

GLYCOSMIS ANGUSTIFOLIA; RUTACEAE; LEAVES; METHYLTHIOPROPENOIC ACID AMIDES; SULFONES; CHEMOSYSTEMATICS;

D O I：

10.1016/S0031-9422(00)90403-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Seven new sulphones derived from methylthiopropenoic acid amides have been isolated as dominant components from the methanolic leaf extract of Glycosmis angustifolia collected in Sri Lanka. All derivatives contained substituted phenethylamine moieties with prenyloxy (dambullins) or geranyloxy groups (gerambullins) in the paraposition. Additional oxidation of the geranyl side chain leads to a diol (gerambullindiol) and to ketones (methylgerambullone and methylisogerambullone). The major component, methyldambullin, exhibited moderate antifungal activity.

引用

页码：1305 / 1310

页数：6

共 8 条

[1] ALKALOIDS OF LEAVES OF GLYCOSMIS-BILOCULARIS [J].