MEASUREMENT OF LIPOPHILICITY BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY - COMPARISON WITH CALCULATED LIPOPHILICITY VALUES

被引：28

作者：

SABATKA, JJ

MINICK, DJ

SHUMAKER, TK

HODGSON, GL

BRENT, DA

机构：

来源：

JOURNAL OF CHROMATOGRAPHY | 1987年 / 384卷

关键词：

D O I：

10.1016/S0021-9673(01)94682-5

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

引用

收藏

页码：349 / 356

页数：8

相关论文

共 10 条

[1] A SIMPLIFIED HIGH-PRESSURE LIQUID-CHROMATOGRAPHY METHOD FOR DETERMINING LIPOPHILICITY FOR STRUCTURE ACTIVITY RELATIONSHIPS
BRENT, DA
SABATKA, JJ
MINICK, DJ
HENRY, DW
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (07) : 1014 - 1020
[2] DETERMINATION OF THERMODYNAMICS OF HYDROXYL AND CARBOXYL GROUPS IN SOLUTIONS OF DRUG MOLECULES
DAVIS, SS
[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1973, 25 (12) : 982 - 992
[3] EVALUATION OF A SIMPLE HPLC CORRELATION METHOD FOR THE ESTIMATION OF THE OCTANOL-WATER PARTITION-COEFFICIENTS OF ORGANIC-COMPOUNDS
HAKY, JE
YOUNG, AM
[J]. JOURNAL OF LIQUID CHROMATOGRAPHY, 1984, 7 (04): : 675 - 689
[4] Hansch C, 1979, SUBSTITUENT CONSTANT
[5] PARTITION COEFFICIENTS AND THEIR USES
LEO, A
HANSCH, C
ELKINS, D
[J]. CHEMICAL REVIEWS, 1971, 71 (06) : 525 - +
[6] SORPTION BEHAVIOR OF ALKYL BONDED PHASES IN REVERSE-PHASE, HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY
LOCHMULLER, CH
WILDER, DR
[J]. JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1979, 17 (10) : 574 - 579
[7] DISTRIBUTION PHENOMENA OF MOBILE-PHASE COMPONENTS AND DETERMINATION OF DEAD VOLUME IN REVERSED-PHASE LIQUID-CHROMATOGRAPHY
MCCORMICK, RM
KARGER, BL
[J]. ANALYTICAL CHEMISTRY, 1980, 52 (14) : 2249 - 2257
[8] STUDIES OF HYDROGEN-BONDED COMPLEX FORMATION WITH P-FLUOROPHENOL .V. LINEAR FREE ENERGY RELATIONSHIPS WITH OH REFERENCE ACIDS
TAFT, RW
GURKA, D
JORIS, L
SCHLEYER, PV
RAKSHYS, JW
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1969, 91 (17) : 4801 - &
[9] SIMPLE PROCEDURE FOR DETERMINING OCTANOL AQUEOUS PARTITION, DISTRIBUTION, AND IONIZATION COEFFICIENTS BY REVERSED-PHASE HIGH-PRESSURE LIQUID-CHROMATOGRAPHY
UNGER, SH
COOK, JR
HOLLENBERG, JS
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1978, 67 (10) : 1364 - 1367
[10] YAMAGAMI C, 1984, CHEM PHARM BULL, V32, P4994