CONCENTRATIONS OF 6-OXO-PROSTAGLANDIN F1-ALPHA IN THE MATERNAL AND FETAL PLASMA OF SHEEP DURING SPONTANEOUS AND INDUCED PARTURITION

被引：18

作者：

MITCHELL, MD

ANDERSON, ABM

BRUNT, JD

CLOVER, L

ELLWOOD, DA

ROBINSON, JS

TURNBULL, AC

机构：

来源：

JOURNAL OF ENDOCRINOLOGY | 1979年 / 83卷 / 02期

关键词：

D O I：

10.1677/joe.0.0830141

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The concentrations of 6-oxo-prostaglandin F(1α) (6-oxo-PGF(1α) have been determined in maternal and foetal plasma from none chronically catheterized sheep during late pregnancy and parturition. Labour occurred either spontaneously (three sheep) or was induced by continuous intrafoetal infusion of Synacthen (ACTH 1-24; 0.24 mg/24 hr three sheep) or dexamethasone (1 mg/24 hr; three sheep). During spontaneous and Synacthen-induced parturition, concentrations of 6-oxo-PGF(1α) in maternal and foetal plasma remained at basal levels until 24 hr before delivery. At varying times during the 24 hr before delivery, levels of 6-oxo-PGF(1α) in maternal and foetal plasma were generally increased. When parturition was induced with dexamethasone, however, no increase was observed in the foetal plasma although the concentration of 6-oxo-PGF(1α) in maternal plasma was raised close to delivery.

引用

页码：141 / 148

页数：8

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